Is PIGD a legitimate motor subtype in Parkinson disease?
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چکیده
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Is PIGD a legitimate motor subtype in Parkinson disease?
Parkinson disease is a chronic progressive syndrome with a broad array of clinical features. Different investigators have suggested the heterogeneous motor manifestations of early Parkinson disease can be conceptualized through a taxonomy of clinical subtypes including tremor-predominant and postural instability and gait difficulty-predominant subtypes. Although it is theoretically valuable to ...
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Parkinson's disease (PD) is one of most disabling disorders of the central nervous system. The motor symptoms of Parkinson's disease: shaking, rigidity, slowness of movement, postural instability and difficulty with walking and gait, are difficult to measure. When disease symptoms become more pronounced, the patient experiences difficulties with hand function and walking, and is prone to falls....
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Background. Previous surveys have shown that motor deficits precede the classical motor symptoms seen in Parkinson’s disease (PD) and that physical exercise may have beneficial effects on PD. Objectives. Here, we evaluated the potential of voluntary exercise to improve motor deficit in experimentally-induced Parkinson’s disease (6-OHDA) rats. Methods. Forty adult Wistar rats were ...
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ژورنال
عنوان ژورنال: Annals of Clinical and Translational Neurology
سال: 2016
ISSN: 2328-9503,2328-9503
DOI: 10.1002/acn3.312